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Naringenin derivative diethyl (5,4′-dihydroxy flavanone-7-yl) phosphate inhibits cell growth and induces apoptosis in A549 human lung cancer cells

✍ Scribed by Jung-Hee Kim; Heejong Kim; Yesol Bak; Jeong-Woo Kang; Dong Hun Lee; Man Sub Kim; Yun Sun Park; Eun-Jin Kim; Kang-Yeoun Jung; Yoongho Lim; Jintae Hong; Do-Young Yoon


Book ID
113112019
Publisher
The Korean Society for Applied Biological Chemistry
Year
2012
Tongue
English
Weight
584 KB
Volume
55
Category
Article
ISSN
1738-2203

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While TRAIL is relatively non-toxic to normal cells, it can selectively induce apoptosis in many types of transformed cells. Nevertheless, some non-small cell lung cancer (NSCLC) cells are particularly resistant to the effects of TRAIL. Here, we report that in combination with naringenin exposure to