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Naphthalene Cytotoxicity of Differentiating Clara Cells in Neonatal Mice

✍ Scribed by M.Voit Fanucchi; Alan R. Buckpitt; Mary E. Murphy; Charles G. Plopper


Book ID
112266386
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
628 KB
Volume
144
Category
Article
ISSN
0041-008X

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## Abstract The IMP dehydrogenase inhibitor, tiazofurin (TR)‐2‐β‐D‐ribofuranosylthiazole‐4‐carboxamide, which exhibited oncolytic activity in patients with chronic myelogenous leukaemia (CML) in blast crisis was found to inhibit the growth of human neuroblastoma SK‐N‐SH cells with an IC~50~ of 4.2