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Nanoscale Metal–Organic Frameworks for the Co-Delivery of Cisplatin and Pooled siRNAs to Enhance Therapeutic Efficacy in Drug-Resistant Ovarian Cancer Cells

✍ Scribed by He, Chunbai; Lu, Kuangda; Liu, Demin; Lin, Wenbin


Book ID
127107408
Publisher
American Chemical Society
Year
2014
Tongue
English
Weight
371 KB
Volume
136
Category
Article
ISSN
0002-7863

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Nanoscale Metal–Organic Frameworks for t
✍ He, Chunbai; Lu, Kuangda; Liu, Demin; Lin, Wenbin 📂 Article 📅 2014 🏛 American Chemical Society 🌐 English ⚖ 371 KB

Ovarian cancer is the leading cause of death among women with gynecological malignancies. Acquired resistance to chemotherapy is a major limitation for ovarian cancer treatment. We report here the first use of nanoscale metal-organic frameworks (NMOFs) for the co-delivery of cisplatin and pooled sma