In this report, we applied in situ atomic force microscopy (AFM) to study the dynamic process of disassembly-assembly of a-synuclein (a-Syn) fibrils in different solutions. Most of the mica-adsorbed a-Syn fibrils disassemble into small particles step-by-step on the mica surface in diluted solutions,
Nanoprobing of α-synuclein misfolding and aggregation with atomic force microscopy
✍ Scribed by Junping Yu; Julia Warnke; Yuri L. Lyubchenko
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 734 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1549-9634
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