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Nanoparticles can cause DNA damage across a cellular barrier

โœ Scribed by Bhabra, Gevdeep; Sood, Aman; Fisher, Brenton; Cartwright, Laura; Saunders, Margaret; Evans, William Howard; Surprenant, Annmarie; Lopez-Castejon, Gloria; Mann, Stephen; Davis, Sean A.


Book ID
109942005
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
548 KB
Volume
4
Category
Article
ISSN
1748-3387

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Thresholds for indirect DNA damage acros
โœ Michael C. Parry; Gevdeep Bhabra; Aman Sood; Filipa Machado; Laura Cartwright; M ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 841 KB

Cobalt-chromium particles and ions can induce indirect DNA damage and chromosome aberrations in human cells on the other side of a cellular barrier in tissue culture. This occurs by intercellular signalling across the barrier. We now show that the threshold for this effect depends on the metal form