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NANOG promotes cancer stem cell characteristics and prostate cancer resistance to androgen deprivation

โœ Scribed by Jeter, C R; Liu, B; Liu, X; Chen, X; Liu, C; Calhoun-Davis, T; Repass, J; Zaehres, H; Shen, J J; Tang, D G


Book ID
109972800
Publisher
Nature Publishing Group
Year
2011
Tongue
English
Weight
998 KB
Volume
30
Category
Article
ISSN
0950-9232

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BACKGROUND. Increased expression of caveolin has been associated with prostate cancer progression. In a mouse reconstitution model of prostate cancer, expression of caveolin was inversely related to androgen sensitivity: androgen independent clones had high caveolin expression; low caveolin expressi