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Nanoformulated Copper/Zinc Superoxide Dismutase Increases Neuronal Uptake Via Active Endocytosis

โœ Scribed by Erin G. Rosenbaugh; Devika S. Manickam; Elena V. Batrakova; Alexander V. Kabanov; Matthew C. Zimmerman


Book ID
113631764
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
178 KB
Volume
49
Category
Article
ISSN
0891-5849

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## Abstract The mechanism of growth inhibition mediated by tumor necrosis factor (TNF) is unclear. Since recent data strongly suggested that generation of superoxide is a key step in cytotoxicity of TNF, we reasoned that cells expressing high levels of enzymes that degrade superoxide radicals would