✦ LIBER ✦

Nanofibrous Poly(lactic acid)/Hydroxyapatite Composite Scaffolds for Guided Tissue Regeneration

✍ Scribed by Sung In Jeong; Eun Kyoung Ko; Jungsuk Yum; Chul Ho Jung; Young Moo Lee; Heungsoo Shin

Publisher: John Wiley and Sons
Year: 2008
Tongue: English
Weight: 384 KB
Volume: 8
Category: Article
ISSN: 1616-5187
DOI: 10.1002/mabi.200700107

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The production of nanofibrous PLA/HA composite scaffolds is described. The morphological, mechanical, surface, and thermal properties of the composites were extensively investigated. The results show that the mixture of PLA and HA formed smooth nanofibers without lumps. The incorporation of HA increased the mechanical strength of the nanofibers and changed the morphology, increasing the mean fiber diameter and pore size. Surface and internal properties confirmed that HA was homogeneously distributed inside the nanofibers and oriented towards their surface. The nanofiber composites allowed the adhesion and proliferation of pre‐osteoblasts for up to 3 weeks.

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