Silica sulfuric acid: an efficient and r
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Peyman Salehi; Minoo Dabiri; Mohammad Ali Zolfigol; Mohammad Ali Bodaghi Fard
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Article
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2003
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Elsevier Science
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French
⚖ 91 KB
Silica sulfuric acid efficiently catalyzes the three-component Biginelli reaction between an aldehyde, a b-dicarbonyl compound and urea or thiourea in refluxing ethanol to afford the corresponding dihydropyrimidinones in high yields. The catalyst is reusable and can be applied several times without