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Naloxone, tardive dyskinesia, and endogenous beta-endorphin

✍ Scribed by Dean Reker; Brian Anderson; Charles Yackulic; Thomas B. Cooper; Miriam Banay-Schwartz; Carlos Leon; Jan Volavka

Book ID
119094329
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
287 KB
Volume
7
Category
Article
ISSN
0165-1781

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## Abstract The effects of both opiate agonists and the opiate antagonist naloxone were examined in a rodent model of tardive dyskinesia (TD). Chronic (˜20 weeks) administration of fluphenazine resulted in the emergence of vacuous chewing mouth movements (VCMs), a response which may be a useful mod