Long-term treatment with levodopa in Parkinson's disease results in the development of motor fluctuations, including reduced duration of antiparkinsonian action and involuntary movements, i.e., levodopa-induced dyskinesia. Cannabinoid receptors are concentrated in the basal ganglia, and stimulation
Naloxone reduces levodopa-induced dyskinesias and apomorphine-induced rotations in primate models of parkinsonism
✍ Scribed by R. Klintenberg; P. Svenningsson; L. Gunne; P. E. Andrén
- Publisher
- Springer
- Year
- 2002
- Tongue
- English
- Weight
- 419 KB
- Volume
- 109
- Category
- Article
- ISSN
- 1435-1463
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