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Naloxone effects on serum growth hormone and prolactin in man

✍ Scribed by David Janowsky; Lewis Judd; Leighton Huey; Norton Roitman; Donal Parker

Publisher
Springer
Year
1979
Tongue
English
Weight
277 KB
Volume
65
Category
Article
ISSN
0033-3158

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✦ Synopsis

Endogenous and exogenous opiate-like compounds have been found to cause increased serum growth hormone and prolactin levels in animals, and, in some cases, humans. Naloxone, a relatively specific narcotic antagonist, decreases serum prolactin and growth hormone levels in animals. Naloxone (20 mg IV) did not significantly alter serum prolactin levels and, minimally but not significantly, increased growth hormone levels in humans to whom it was administered.

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