✦ LIBER ✦

Naked DNA expressing two isoforms of hepatocyte growth factor induces collateral artery augmentation in a rabbit model of limb ischemia

✍ Scribed by Hahn, W; Kim, D-S; Pyun, W-B; Yoo, W-S; Lee, S-D; Won, J-H; Rho, B-S; Park, Z-Y; Kim, J-M; Kim, S

Book ID: 109855361
Publisher: Nature Publishing Group
Year: 2010
Tongue: English
Weight: 748 KB
Volume: 17
Category: Article
ISSN: 0969-7128
DOI: 10.1038/gt.2010.101

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

A phase I clinical study of naked DNA ex

A phase I clinical study of naked DNA expressing two isoforms of hepatocyte growth factor to treat patients with critical limb ischemia

✍ Yongquan Gu; Jian Zhang; Lianrui Guo; Shijun Cui; Xuefeng Li; Dayou Ding; Jong-M 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 254 KB

## Abstract ## Background The purpose of the present phase I clinical trial was to evaluate the safety, tolerability, and preliminary efficacy of naked DNA therapy expressing two isoforms of hepatocyte growth factor (pCK‐HGF‐X7) in critical limb ischemia (CLI) patients. ## Materials and methods

Enhanced cardioprotective effects by coe

Enhanced cardioprotective effects by coexpression of two isoforms of hepatocyte growth factor from naked plasmid DNA in a rat ischemic heart disease model

✍ Woong Hahn; Wook-Bum Pyun; Dong-Sik Kim; Won-Sun Yoo; Sung-Dong Lee; Jung-Hee Wo 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 288 KB

## Abstract ## Background The therapeutic potential of pCK‐HGF‐X7, a naked DNA designed to express two isoforms of hepatocyte growth factor (HGF~723~ and HGF~728~), was studied in the rat ischemic heart disease model. ## Methods First, the kinetics of gene expression was examined by injecting pC