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Na+/H+exchange is increased in sickle cell anemia and young normal red cells

โœ Scribed by Mitzy Canessa; Mary E. Fabry; Sandra M. Suzuka; Kevin Morgan; Ronald L. Nagel


Publisher
Springer
Year
1990
Tongue
English
Weight
865 KB
Volume
116
Category
Article
ISSN
0022-2631

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Na+/H+ exchanger activity is increased i
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## Abstract Multidrug resistant (MDR) tumor cells exhibit an altered pH gradient across different cell compartments, which favors a reduced intracellular accumulation of antineoplastic drugs and a decreased therapeutic effect. In our study, we have observed that the activity and expression of Na^+^