## Abstract Retinitis pigmentosa (RP) is a prevalent cause of blindness caused by a large number of different mutations in many different genes. The mutations result in rod photoreceptor cell death, but it is unknown why cones die. In this study, we tested the hypothesis that cones die from oxidati
β¦ LIBER β¦
NADPH oxidase plays a central role in cone cell death in retinitis pigmentosa
β Scribed by Shinichi Usui; Brian C. Oveson; Sun Young Lee; Young-Joon Jo; Tsunehiko Yoshida; Akiko Miki; Katsuaki Miki; Takeshi Iwase; Lili Lu; Peter A. Campochiaro
- Book ID
- 111183523
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 818 KB
- Volume
- 110
- Category
- Article
- ISSN
- 0022-3042
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## Abstract Retinitis pigmentosa (RP) is a heterogeneous group of diseases in which one of a wide variety of mutations selectively causes rod photoreceptor cell death. After rods die, cone photoreceptors gradually die resulting in blindness. Antioxidants reduce cone cell death in __rd1__/__rd1__ mi
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