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NAD+ and sirtuins in aging and disease

โœ Scribed by Imai, Shin-ichiro; Guarente, Leonard


Book ID
122950747
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
617 KB
Volume
24
Category
Article
ISSN
0962-8924

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NAD+ and sirtuins in aging and disease
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Nicotinamide adenine dinucleotide (NAD+) is a classical coenzyme mediating many redox reactions. NAD+ also plays an important role in the regulation of NAD+-consuming enzymes, including sirtuins, poly-ADP-ribose polymerases (PARPs), and CD38/157 ectoenzymes. NAD+ biosynthesis, particularly mediated

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