## Abstract Objective measures of motor impairment may improve the sensitivity and reliability of motor end points in clinical trials. In Huntington's disease, involuntary choreatic movements are one of the hallmarks of motor dysfunction. Chorea is commonly assessed by subitems of the Unified‐Hunti
Nabilone increases choreatic movements in Huntington's disease
✍ Scribed by Kirsten R. Müller-Vahl; Udo Schneider; Hinderk M. Emrich
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 409 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0885-3185
No coin nor oath required. For personal study only.
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## Abstract Pilot study of nabilone in Huntington's disease (HD). Double‐blind, placebo‐controlled, cross‐over study of nabilone versus placebo. Primary outcome, Unified Huntington's Disease Rating Scale (UHDRS) total motor score. Secondary measures: UHDRS subsections for chorea, cognition and beha
Clinical rating, caudate atrophy, disturbed movement performance, neuropsychological testing, and age-related genetic disease load (CAG index) are tools that reflect impairment after onset of Huntington's disease (HD). Objectives were to compare scored HD symptoms, results of neuropsychological test