Na+-overload during ischemia and reperfusion in rat hearts: comparison of the Na+/H+-exchange blockers EIPA, HOE642 and EMD96785

Comparison of the protective actions of

Comparison of the protective actions of Na+/H+ and Na+/Ca2+ exchange inhibitors in ischemic/reperfused rat hearts

✍ Hiroko Tachibana; Yoshinori Kitano; Mitsuo Ishii; Mitsuyoshi Ninomiya; Kazumi Iw 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 201 KB

The protective effects of the Na + /H + exchange inhibitors amiloride, EIPA (5-(N-ethyl-Nisopropyl)-amiloride), and HOE 694 (3-methylsulfonyl-4-(1-piperidino) benzoyl-guanidine) and the Na + / Ca 2+ exchange inhibitor, DCB (3,4-Dichlorobenzamil) on ischemia (30 min) / reperfusion (30 min) injury wer