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Na+ dependent glutamate transporters (EAAT1, EAAT2, and EAAT3) in primary astrocyte cultures: effect of oxidative stress

✍ Scribed by Vicente J Miralles; Itziar Martı́nez-López; Rosa Zaragozá; Elisa Borrás; Concha Garcı́a; Federico V Pallardó; Juan R Viña

Book ID: 113997643
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 688 KB
Volume: 922
Category: Article
ISSN: 0006-8993
DOI: 10.1016/s0006-8993(01)03124-9

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## Abstract Transporters for L‐glutamate (excitatory amino acid transporters; EAATs), localized to astrocytes, are involved intimately in intermediary metabolism within the brain. Because (2__S__,4__R__)‐4‐methylglutamate (4MG) has affinity for glial EAATs, we employed [^3^H]4MG to define the chara