The CHO cell line has achieved considerable commercial importance as a vehicle for the production of human therapeutic proteins, but is known to lack a functional copy of the gene coding for α2,6-sialyltransferase (EC 2.4.99.1). The cDNA for rat α2,6-ST was expressed in a recombinant CHO cell line m
✦ LIBER ✦
Na-butyrate increases the production and α2,6-sialylation of recombinant interferon-γ expressed by α2,6- sialyltransferase engineered CHO cells
✍ Scribed by Damien Lamotte; Lorraine Buckberry; Lucia Monaco; Marco Soria; Nigel Jenkins; Jean-Marc Engasser; Annie Marc
- Book ID
- 110258319
- Publisher
- Springer
- Year
- 1999
- Tongue
- English
- Weight
- 105 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0920-9069
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