✦ LIBER ✦

N(7)-protonation induced conformational flipping in hypermodified nucleic acid bases N6-(N-threonylcarbonyl)adenine and its 2-methylthio- or N(6)-methyl- derivatives

✍ Scribed by Uddhavesh B. Sonavane; Kailas D. Sonawane; Annie Morin; Henri Grosjean; Ravindra Tewari

Publisher: John Wiley and Sons
Year: 1999
Tongue: English
Weight: 194 KB
Volume: 75
Category: Article
ISSN: 0020-7608
DOI: 10.1002/(sici)1097-461x(1999)75:3<223::aid-qua12>3.0.co;2-e

No coin nor oath required. For personal study only.

✦ Synopsis

3Ј-side with four bases of mRNA, permitting an altered selection of the codon triplet. 6 6

Ž . However, another derivative, m tc Ade, because of the methyl group replacing the N 6 hydrogen, cannot base pair with uridine and should maintain the reading frame Ž .