𝔖 Bobbio Scriptorium
✦   LIBER   ✦

N1,N7-expeditious dialkylation of cyclen (1,4,7,10-tetraazacyclododecane). An astonishing reactivity of cyclen tricarbonyl molybdenum and chromium complexes

✍ Scribed by V. Patinec; J.J. Yaouanc; H. Handel; J.C. Clément; H. des Abbayes


Book ID
103110018
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
190 KB
Volume
220
Category
Article
ISSN
0020-1693

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Expeditious N-monoalkylation of 1,4,7,10
✍ Vincenzo Boldrini; Giovanni B Giovenzana; Roberto Pagliarin; Giovanni Palmisano; 📂 Article 📅 2000 🏛 Elsevier Science 🌐 French ⚖ 109 KB

The reaction of cyclen 1 with chloral hydrate aorded exclusively 1,4,7-triformylcyclen 2 in high yield; the triprotected macrocycle was easily alkylated with various electrophiles in good to excellent yields. The alkaline removal of the formyl groups provided a selective entry into N-monosubstituted