N1-allyl-3-substituted-6,7-dimethyl-1,2-dihydro-2-quinoxalinone as key intermediate for new acyclonucleosides and their regioisomer O-analogues

✍ Scribed by Ibrahim A. I. Ali; Walid Fathalla

• Book ID: 102846358
• Publisher: John Wiley and Sons
• Year: 2006
• Tongue: English
• Weight: 636 KB
• Volume: 17
• Category: Article
• ISSN: 1042-7163
• DOI: 10.1002/hc.20203

✦ Synopsis

Abstract

The key intermediates allyloxyquinoxaline 2a–c and N‐allylquinoxaline 3a–c were used to synthesize a number of acyclonucleosides whose chemical modifications include quinoxaline ring and the acyclic part is either N^1^‐propanediol or 3‐hydroxy‐ propyl substituents and their O‐analogues. These compounds were characterized by elemental analysis, MALDI MS, and NMR data. © 2006 Wiley Periodicals, Inc. Heteroatom Chem 17:280–288, 2006; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20203