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N011 Therapeutic drug monitoring of thiopurine metabolites in patients with inflammatory bowel disease (IBD) in a Dutch peripheral hospital. Indications and therapeutic consequences

โœ Scribed by Theeuwen, R.; Alleman, M.; Abraham, S.; Ong, R.; Vu, M.

Book ID
122147066
Publisher
Oxford University Press
Year
2014
Tongue
English
Weight
47 KB
Volume
8
Category
Article
ISSN
1873-9946

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Clinical usefulness of therapeutic drug
Clinical usefulness of therapeutic drug monitoring of thiopurines in patients with inadequately controlled inflammatory bowel disease
โœ Melissa L. Haines; Yousef Ajlouni; Peter M. Irving; Miles P. Sparrow; Rosemary R ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 155 KB ๐Ÿ‘ 2 views

Background: Circulating concentrations of 6-thioguanine nucleotide (6-TGN) and 6-methyl mercaptopurine (6-MMP) are associated with thiopurine efficacy and may predict toxicity. This study aimed to examine retrospectively the utility of measuring metabolite concentrations in patients with inflammator