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(−)-N-(tert-Butoxy­carbon­yl)-l-proline-2-thio­amide (Boc-l-Pro-thio­amide)

✍ Scribed by Oku, Hiroyuki ;Yoshinari, Takamasa ;Yamada, Keiichi ;Katakai, Ryoichi

Publisher
International Union of Crystallography
Year
2006
Tongue
English
Weight
234 KB
Volume
62
Category
Article
ISSN
1600-5368

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✦ Synopsis

Crystals of the title compound, C 10 H 18 N 2 O 2 S, which is an enantiopure N-protected l-prolinethioamide, were successfully grown from a tetrahydrofuran solution. Intermolecular N-HÁ Á ÁO hydrogen bonds are observed between thioamide -NH 2 and Boc-carbonyl C O groups, but the thioamide C S group is not involved in hydrogen bonding.

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A synthetic fragment of a cyclic depsipe
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✍ Oku, Hiroyuki ;Yamada, Keiichi ;Katakai, Ryoichi 📂 Article 📅 2004 🏛 International Union of Crystallography 🌐 English ⚖ 250 KB

Crystals of the title compound, C 17 H 30 N 2 O 7 , were successfully grown from ethyl acetate at room temperature. In the crystal structure, a free carboxylic acid group is found at the terminal C atom. The free acid ÐOH group contributes to a hydrogenbond network, together with two NÐHÁ Á ÁO inter