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N-terminal region of α-synuclein is essential for the fatty acid-induced oligomerization of the molecules

✍ Scribed by Hiroki Karube; Masahiro Sakamoto; Shigeki Arawaka; Susumu Hara; Hiroyasu Sato; Chang-Hong Ren; Saori Goto; Shingo Koyama; Manabu Wada; Toru Kawanami; Keiji Kurita; Takeo Kato


Book ID
113621035
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
528 KB
Volume
582
Category
Article
ISSN
0014-5793

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The N-terminal region of HtrA heat shock
✍ Joanna Skórko-Glonek; Dorota Żurawa; Fabio Tanfani; Andrea Scirè; Alicja Wawrzyn 📂 Article 📅 2003 🏛 Elsevier Science 🌐 English ⚖ 430 KB

HtrA heat shock protease is highly conserved in evolution, and in Escherichia coli, it protects the cell by degradation of proteins denatured by heat and oxidative stress, and also degrades misfolded proteins with reduced disulfide bonds. The mature, 48-kDa HtrA undergoes partial autocleavage with f