N-terminal brain natriuretic propeptide levels correlate with procalcitonin and C-reactive protein levels in septic patients

✍ Scribed by Mariusz Piechota; Maciej Banach; Robert Irzmański; Małgorzata Misztal; Jacek Rysz; Marcin Barylski; Magdalena Piechota-Urbańska; Jan Kowalski; Lucjan Pawlicki

• Book ID: 111490353
• Publisher: SP Versita
• Year: 2007
• Tongue: English
• Weight: 345 KB
• Volume: 12
• Category: Article
• ISSN: 1425-8153
• DOI: 10.2478/s11658-006-0062-y

✦ Synopsis

Abstract

The aim of this study was to find the relationship between N-terminal brain natriuretic propeptide (NT-proBNP), procalcitonin (PCT) and C-reactive protein (CRP) plasma concentrations in septic patients. This was a prospective study, performed at Medical University Hospital No. 5 in łódź. Twenty patients with sepsis and severe sepsis were included in the study. N-terminal brain natriuretic propeptide, procalcitonin and C-reactive protein concentrations, and survival were evaluated. In the whole studied group (128 measurements), the mean NT-proBNP, procalcitonin and C-reactive protein concentrations were, respectively: 140.80±84.65 pg/ml, 22.32±97.41 ng/ml, 128.51±79.05 mg/l. The correlations for the NT-proBNP level and procalcitonin and C-reactive protein levels were 0.3273 (p<0.001) and 0.4134 (p<0.001), respectively. NT-proBNP levels correlate with PCT and CRP levels in septic patients. In the survivor subgroup, the mean NT-proBNP plasma concentrations were significantly lower than in the non-survivor subgroup.