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N-Sulfonyl hydroxamate derivatives as inhibitors of class II fructose-1,6-diphosphate aldolase

✍ Scribed by Sabine Gavalda; Rémi Braga; Chantal Dax; Alain Vigroux; Casimir Blonski


Book ID
108073804
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
105 KB
Volume
15
Category
Article
ISSN
0960-894X

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## Abstract Treatment of the Class II fructose‐1,6‐bisphosphate aldolase of __Escherichia coli__ with the arginine‐specific α‐dicarbonyl reagents, butanedione or phenylglyoxal, results in inactivation of the enzyme. The enzyme is protected from inactivation by the substrate, fructose 1,6‐bisphospha