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N-Sulfonyl Homoserine Lactones as Antagonists of Bacterial Quorum Sensing.

✍ Scribed by Sandra Castang; Bernard Chantegrel; Christian Deshayes; Rene Dolmazon; Patrice Gouet; Richard Haser; Sylvie Reverchon; William Nasser; Nicole Hugouvieux-Cotte-Pattat; Alain Doutheau


Publisher
John Wiley and Sons
Year
2005
Weight
18 KB
Volume
36
Category
Article
ISSN
0931-7597

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## Abstract Bacteria can coordinate group behavior using chemical signals in a process called quorum sensing (QS). The QS system in the opportunistic pathogen __Pseudomonas aeruginosa__ is largely governed by the LasR receptor and its cognate chemical signal, __N__‐(3‐oxo)‐dodecanoyl L‐homoserine l