N-Substituted tetrahydro-1,3-oxazines and oxazolidines. 1. A new version of the Mannich reaction involving amino alcohols
✍ Scribed by A. G. Korepin; P. V. Galkin; N. M. Glushakova; G. V. Lagodzinskaya; M. V. Loginova; V. P. Lodygina; L. T. Eremenko
- Book ID
- 110275094
- Publisher
- Springer
- Year
- 2001
- Tongue
- English
- Weight
- 282 KB
- Volume
- 50
- Category
- Article
- ISSN
- 1573-9171
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At room temperature, the presence of hydrogen and catalytic amounts of Pd/C induced the formation of 1,3-oxazolidines from nitriles and 1,2-amino alcohols. The subsequent reductive cleavage of the NC-O bond of lhese heterocycles occurred under the same conditions. Thus, this methodology provides a n
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