## Abstract Due to the increasing role of esophageal tumors in human cancer pathology, there is need for animal models evaluating the mechanisms of esophageal carcinogenesis and investigating protective factors toward this disease. Several __N__βnitrosamines have been shown to induce esophageal tum
N-nitrosoheptamethyleneimine-induced pulmonary and esophageal carcinogenesis and effects of concomitant treatment with bleomycin in rats
β Scribed by Yasunori Yoshida; Ryohei Hasegawa; Katsumi Takaba; Katsumi Imaida; Nobuyuki Ito
- Book ID
- 112213522
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 323 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0270-3211
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Bleomycin is an antibiotic used to treat a variety of neoplasms. A major side-effect of bleomycin therapy is the induction of an intense inflammatory response that develops into pulmonary fibrosis. Several studies have shown that certain polyunsaturated fatty acids found in fish oil reduce the infla
It is now accepted that the incidence of esophageal carcinoma is highest in the middle thoracic region. Esophageal carcinoma after gastrectomy, however, has a tendency to develop in the lower thoracic region. These studies suggest a possible correlation between the development of esophageal carcinom