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N, N‘ (4,5-Dihydro-1H-imidazol-2-yl)3-aza-1, 10-decane-diamine and N, N’(4,5-dihydro-1H-imidazol-2-yl)3-aza-1, 10-dodecane-diamine antagonize cell proliferation as selective ligands towards topoisomerase II

✍ Scribed by Rosanna Filosa; Mariafrancesca Buonerba; Roberta Loddo; Bernardetta Busonera; Paolo La Colla; Carmela Saturnino


Book ID
111770463
Publisher
Pharmaceutical Press
Year
2006
Tongue
English
Weight
787 KB
Volume
58
Category
Article
ISSN
2042-7158

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Bis[1-hydroxy-4,4,5,5-tetra­methyl-2-(1,
✍ Chang, Jiu-Li ;Wang, Li-Ya ;Jiang, Kai 📂 Article 📅 2005 🏛 International Union of Crystallography 🌐 English ⚖ 339 KB

In the title complex, [Hg(NO 3 ) 2 (C 10 H 15 N 3 OS) 2 ], the Hg II ion (site symmetry 1) adopts a grossly distorted octahedral geometry by chelation of two neutral Him-thz ligands [Himthz is 2-(2 0 -thiazole)-4,4,5,5-tetramethyldihydro-1H-imidazolyl-1-hydroxy] through their thiazole N atoms [Hg-N