PCNU, a chloroethylnitrosourea with high alkylating activity, low carbamoylating activity, optimal octanol: water partition coefficient and broad activity in animal systems, was administered to 32 evaluable patients with measurable metastatic melanoma by brief intravenous infusions every six weeks.
N-Methylformamide in Advanced Squamous Cancer of the Uterine Cervix: An Eastern Cooperative Oncology Group Phase II Trial
β Scribed by Lakshmi Rajdev; Zi-Fan Yu; Scott Wadler; Edie Weller; S. Benham Kahn; Douglass Tormey; Roland Skeel; Peter H. Wiernik
- Book ID
- 110294216
- Publisher
- Springer US
- Year
- 2001
- Tongue
- English
- Weight
- 61 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0167-6997
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## Abstract ## BACKGROUND The current study was conducted to evaluate the antitumor activity and toxicity of gemcitabine in patients with advanced sarcoma. ## METHODS Twentyβfive patients with advanced sarcomas, who previously were untreated for metastatic disease, were treated on an Eastern Coo