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N-methylation and N-oxidation of the less reactive nitrogen atom of a 2,3′-bipyridine. Two general methods for polyazines

✍ Scribed by John A. Zoltewicz; Michael P. Cruskie Jr.

Book ID: 103396865
Publisher: Elsevier Science
Year: 1995
Tongue: French
Weight: 582 KB
Volume: 51
Category: Article
ISSN: 0040-4020
DOI: 10.1016/0040-4020(95)00074-i

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## Abstract Sumitriptan (1), a non‐selective 5‐HT~1B/1D~ agonist is an effective therapeutic agent for the acute treatment of migraine, but it is contraindicated for use in patients with known heart disease. The first Selective Serotonin One F Receptor Agonist (SSOFRA), 5‐(4′‐fluorobenz‐amido)‐3‐(_