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N -Methylamino acids in peptide synthesis. V. The synthesis of N - tert -butyloxycarbonyl, N -methylamino acids by N -methylation

✍ Scribed by Cheung, S. T.; Benoiton, N. Leo


Book ID
121271039
Publisher
NRC Research Press
Year
1977
Tongue
French
Weight
332 KB
Volume
55
Category
Article
ISSN
0008-4042

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residue is treated with ice. The aqueous suspension is extracted with benzene (about 300 ml), and the organic phase is at once chromatographed on acid A1203. Benzene (1000 ml) is used for elution. After evaporation of the solvent the residue is taken up in ether, and the solution is decanted at once