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N-methyl-d-aspartate receptor-mediated, prolonged afterdischarges of CA1 pyramidal cells following transient cerebral ischemia in the rat hippocampus in vivo

✍ Scribed by Shuhei Miyazaki; Yoichi Katayama; Makoto Furuichi; Tsuneo Kano; Atsuo Yoshino; Takashi Tsubokawa


Book ID
113127079
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
493 KB
Volume
657
Category
Article
ISSN
0006-8993

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## Abstract Zinc is an endogenous N‐methyl‐D‐aspartate (NMDA) receptor blocker. It is possible that zinc‐mediated modification of hippocampal CA1 long‐term potentiation (LTP) is linked to the expression of NMDA receptor subunits, which varies with postnatal development. In the present study, the ef