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N-Methyl-D-aspartate receptor activation inhibits protein synthesis in cortical neurons independently of its ionic permeability properties

✍ Scribed by C Gauchy; A.C Nairn; J Glowinski; J Prémont


Book ID
117490665
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
350 KB
Volume
114
Category
Article
ISSN
0306-4522

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## Abstract The N‐methyl‐D‐aspartate receptor (NMDAR) is fundamental to normal and pathological functioning of neurons. The receptor subunits are N‐glycosylated proteins synthesized in the endoplasmic reticulum (ER) that fold, mature, and oligomerize as they transit through the secretory pathway. A