N-methyl-3-(1-hydroxy-5-[123I]iodopent-4-enyl)-4-acetoxypiperidine, a novel candidate of acetylcholinesterase activity imaging agent

Synthesis of [123I]tert-butyl 8-iodo-5,6

Synthesis of [123I]tert-butyl 8-iodo-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine 3-carboxylate, a potential SPECT imaging agent for diazepam-insensitive (DI) benzodiazepine receptors

✍ Xiao-Shu He; Dorota Matecka; Kan Sam Lee; Zi-Qiang Gu; Kenner C. Rice; Garry Won 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 French ⚖ 355 KB 👁 1 views

## Abstract [^123^I]__tert__‐Butyl 8‐iodo‐5,6‐dihydro‐5‐methyl‐6‐oxo‐4__H__‐imidazo [1,5‐a][1,4]benzodiazepine 3‐carboxylate ([^123^I]3), a high affinity and selective radioligand for the diazepam insensitive (DI) benzodiazepine receptor was synthesized in 2 steps from __tert__‐butyl 8‐bromo‐5,6‐di