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N-linked glycosylation of the bone morphogenetic protein receptor type 2 (BMPR2) enhances ligand binding

โœ Scribed by Lowery, Jonathan W.; Amich, Jose M.; Andonian, Alex; Rosen, Vicki


Book ID
121588989
Publisher
Springer
Year
2013
Tongue
English
Weight
519 KB
Volume
71
Category
Article
ISSN
1420-682X

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## Abstract Bone morphogenetic protein (BMP)โ€2 plays an important role in bone growth and regeneration; however, BMPโ€2 is easily lost by diffusion through body fluid and has some inhibitory pathways. To address this problem, we previously immobilized recombinant human BMPโ€2 (rhBMPโ€2) on succinylate