N-Heterocyclic Carbenes: Useful Ligands for the Palladium-Catalysed Direct C5 Arylation of Heteroaromatics with Aryl Bromides or Electron-Deficient Aryl Chlorides
✍ Scribed by Ismail Ozdemir; Yetkin Gök; Özlem Özeroğlu; Murat Kaloğlu; Henri Doucet; Christian Bruneau
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 230 KB
- Volume
- 2010
- Category
- Article
- ISSN
- 1434-1948
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## Abstract A simple and atom‐economical procedure for the regioselective C‐2 or C‐5 arylation of pyrroles __via__ a CH bond activation is reported. Only 0.5–0.01 mol% of commercially available and air‐stable ligand‐free palladium(II) acetate [Pd(OAc)~2~] was employed as the catalyst. The presence
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