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N-Heterocyclic Carbene Catalyzed Reactions of α-Bromo-α,β-unsaturated Aldehydes/α,β-Dibromoaldehydes with 1,3-Dinucleophilic Reagents

✍ Scribed by Prof. Dr. Changsheng Yao; Donglin Wang; Jun Lu; Prof. Dr. Tuanjie Li; Weihui Jiao; Prof. Chenxia Yu


Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
245 KB
Volume
18
Category
Article
ISSN
0947-6539

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Diastereoselective Synthesis of Trifluor
✍ Keiichi Hirano; Isabel Piel; Frank Glorius 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 185 KB

## Abstract The N‐heterocyclic carbene‐catalyzed conjugate umpolung of differently substituted α,β‐unsaturated aldehydes is described. Coupling of these compounds with a variety of trifluoromethylated ketones results in the selective formation of fluorinated γ‐butyrolactones. Using thiazolium‐deriv