A point mutation at Asn-534 that disrupt
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Mikiko Sasayama; Ikuo Shoji; Myrna Adianti; Da-Peng Jiang; Lin Deng; Takafumi Sa
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Article
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2011
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John Wiley and Sons
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English
β 154 KB
## Abstract The molecular basis of antibody neutralization against hepatitis C virus (HCV) is poorly understood. The E2 glycoprotein of HCV is critically involved in viral infectivity through specific binding to the principal virus receptor component CD81, and is targeted by antiβHCV neutralizing a