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N-Functionalization of Azoles Through Coupling Reactions with Alkoxydienyl and Alkoxystyryl Boronic Esters.

✍ Scribed by Annamaria Deagostino; Cristina Prandi; Chiara Zavattaro; Paolo Venturello


Book ID
102009126
Publisher
John Wiley and Sons
Year
2007
Weight
34 KB
Volume
38
Category
Article
ISSN
0931-7597

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N-Functionalization of Azoles through Co
✍ Annamaria Deagostino; Cristina Prandi; Chiara Zavattaro; Paolo Venturello πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 112 KB

## Abstract Alkoxydienyl boronates **1a** and **1b** and alkoxystyryl boronate **2** have been used in various copper mediated cross‐coupling reactions with azoles. A variety of __N__‐alkoxydienyl‐ and __N__‐styrylazoles have been synthesized under mild conditions. The process utilizes Cu(OAc)~2~ i

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## Abstract It is found that K~2~CO~3~/Pd~2~dba~3~‐mediated treatment of the dichloro acid (I) with boronic acids allows selective formation of 2‐arylated derivatives like (III).