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N-Chlorosuccinimide as a versatile reagent for the sulfenylation of ketones: a facile synthesis of α-ketothioethers

✍ Scribed by J.S. Yadav; B.V. Subba Reddy; Ruchi Jain; Gakul Baishya

Publisher
Elsevier Science
Year
2008
Tongue
French
Weight
153 KB
Volume
49
Category
Article
ISSN
0040-4039

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✦ Synopsis

The sulfenylation of ketones having a-hydrogens has been achieved using N-chlorosuccinimide (NCS) under mild reaction conditions to produce a-ketothioethers in excellent yields with high selectivity. The use of NCS makes this method quite simple, convenient and practical.

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