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N-Chloro-2,2-dimethyltaurines: a new class of remarkably stable N-chlorotaurines

✍ Scribed by Lu Wang; Behzad Khosrovi; Ramin Najafi

Book ID: 104095080
Publisher: Elsevier Science
Year: 2008
Tongue: French
Weight: 119 KB
Volume: 49
Category: Article
ISSN: 0040-4039
DOI: 10.1016/j.tetlet.2008.02.038

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✦ Synopsis

The preparation of novel N-chloro-2,2-dimethyltaurine (4) and N,N-dichloro-2,2-dimethyltaurine (5) is described. These 2,2-dimethyltaurines were strategically designed to avoid the hydrolytic dehydrochlorination of N-chlorotaurines. Thus, they possess longterm stability in contrast to the parent N-chlorotaurines, which exhibit broad-spectrum antimicrobial activities.

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