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N-Cadherin Is Involved in Axon-Oligodendrocyte Contact and Myelination

✍ Scribed by Oliver Schnädelbach; Ílknur Özen; Orest W. Blaschuk; Barbara J. Gour; Ronald L. Meyer; James W. Fawcett


Book ID
115637737
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
663 KB
Volume
17
Category
Article
ISSN
1044-7431

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## Abstract One pathological characteristic of Alzheimer's disease (AD) is extensive synapse loss. Presenilin 1 (PS1) is linked to the pathogenesis of early onset familial Alzheimer's disease (FAD) and is localized at the synapse, where it binds N‐cadherin and modulates its adhesive activity. To el