N-Boc-2-stannyloxazolidines Derived from (R)-Phenylglycinol: Preparation, Transmetalation, and Use as Precursors of Enantioenriched (α-Aminoalkyl)triorganostannanes.

Preparation and Transmetallation of Enan

Preparation and Transmetallation of Enantioenriched α-Aminoorganostannanes Derived from N-Boc Phenylglycinol: Application to the Synthesis of Alafosfalin

✍ Vincent Coeffard; Isabelle Beaudet; Michel Evain; Erwan Le Grognec; Jean-Paul Qu 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 358 KB 👁 1 views

## Abstract Enantioenriched tributylstannylated α‐amino alcohols were synthesised by an improved procedure based on ring opening of 2‐tributylstannyloxazolidines. Corresponding α‐amino organolithiums were generated from __O__‐silylated tributylstannylated α‐amino alcohols and trapped with retention