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N-Band polymorphism of human acrocentric chromosomes and its relevance to satellite association

✍ Scribed by Isamu Hayata; Mitsuo Oshimura; Avery A. Sandberg

Publisher: Springer
Year: 1977
Tongue: English
Weight: 371 KB
Volume: 36
Category: Article
ISSN: 0340-6717
DOI: 10.1007/bf00390436

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✦ Synopsis

With the aid of Q- and N-banding techniques we investigated the relationship between the length of satellite stalks, the appearance of N-bands and the frequency of satellite association of individual acrocentric chromosomes in the cells of seven individuals, including one male with a satellited and small Y-chromosomes. The appearance of N-bands, seemed to be a constant and characteristic property of individual acrocentric chromosomes, independent of the status of concentration of the chromosomes at metaphase. The homolog with longer satellite stalks had larger N-bands and participated in satellite association at a higher frequency than the one with shorter stalks. It appeared that N-bands were present along the whole length of the satellite stalk, the size of which could possibly reflect the amount of rDNA present in the nucleolar organizers in human chromosomes.

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