## Abstract For Abstract see ChemInform Abstract in Full Text.
N-Arylation of α-aminoesters with p-tolylboronic acid promoted by copper(II) acetate
✍ Scribed by Patrick Y.S Lam; Damien Bonne; Guillaume Vincent; Charles G Clark; Andrew P Combs
- Book ID
- 104252942
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- French
- Weight
- 256 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0040-4039
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Heteroarylcarboxamides containing a-nitrogens undergo copper-promoted N-phenylation with hypervalent phenyl trimethylsiloxane at room temperature, in the absence of base and in air. Arylboronic acid can substitute for phenyl trimethylsiloxane as the organometalloid. The a-heteroatom chelating effect
Two types of cycloisodityrosines, 11 and 13, were synthesized from commercially available chiral tyrosine derivatives through the copper(II) acetate-DMAP-mediated diaryl ether formation of boronotyrosyltyrosines 8 and 10, respectively.