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N-Allylation of Anilides with Chiral Palladium Catalysts: The First Catalytic Asymmetric Synthesis of Axially Chiral Anilides.

✍ Scribed by Jun Terauchi; Dennis P. Curran


Publisher
John Wiley and Sons
Year
2003
Weight
29 KB
Volume
34
Category
Article
ISSN
0931-7597

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## Abstract Palladium‐catalyzed cross‐coupling of bipyridine __N,N′__‐dioxide 6,6′‐dichloride (__R__~__nap__~__,R__~__pyr__~)‐**1** with the aryl Grignard reagents opened a new approach to axially chiral bipyridine __N,N′‐__dioxides (__R__)‐**2** bearing a variety of aryl groups at the 6 and 6′ pos